San Francisco (SFO)
Santa Cruz (VVI)
*Some restrictions may apply. Round-trip fares per adult, include applicable taxes and fees. Please review our baggage policies, and optional services.
Some flights could be operated by: LATAM Airlines Brazil, LATAM Airlines Colombia, LATAM Airlines Peru, LATAM Airlines Argentina or American Airlines.
Located in the heart of Bolivia, Santa Cruz is one of the world’s fastest-growing cities. Travelers will discover a city filled with must-see attractions, clubs, discos, and restaurants. Book your flight to Santa Cruz with LATAM today and travel in comfort with our ergonomic seats and adjustable headrests.
What to see in Santa Cruz
Start your adventure at the Catedral de Santa Cruz. Climb the church tower for panoramic city views. Then venture into the jungles of Amboro National Park. Hike to cascading waterfalls while immersing yourself in the diverse flora and fauna of three distinct ecosystems. Kaa-Iya National Park is larger than
When to visit Santa Cruz
June, July, and August are the Southern Hemisphere's winter, so they are the coolest and driest months in Santa Cruz. December and January are the rainiest.