Spend a special Thanksgiving with family and friends in South America!
*Some restrictions may apply. Round-trip fares per adult, include applicable taxes and fees. Please review our baggage policies, and optional services.
Some flights could be operated by: LATAM Airlines Brazil, LATAM Airlines Colombia, LATAM Airlines Peru, LATAM Airlines Argentina or American Airlines.
Our most popular US to South America routes
From New York
From Los Angeles
From Other US Locations
Looking for domestic flights within South America?